Clinico-Biochemical and Nephroprotective Effects of Medicinal Herbs on Gentamicin Induced Nephrotoxicity in Wistar Rats
نویسندگان
چکیده
منابع مشابه
Biochemical effects of oleuropein in gentamicin-induced nephrotoxicity in rats
BACKGROUND Oleuropein is a natural antioxidant and scavenging free radicals. In the present study, we examined effect of oleuropein on the paraoxonase 1 (PON1) activity, lipid peroxidation, lipid profile, atherogenic indexes, and relationship of PON1 activity by high-density lipoprotein-cholesterol (HDL-C) and atherogenic indices in gentamicin (GM)-induced nephrotoxicity in rats. METHODS This...
متن کاملEffects of Cinnamon Extract on Curing and Preventing Gentamicin-induced Nephrotoxicity in Immature White Rats
Background and purpose: Gentamicin-induced nephrotoxicity results from the production of reactive oxygen species (ROS) in the kidneys, and since cinnamon has antioxidant properties, this research studied the effects of cinnamon extract on the prevention and treatment of gentamicin-induced toxicity in immature white rats.Materials and methodology: in this study 36 immature female Wistar rats wer...
متن کاملProtective effect of crocin on gentamicin-induced nephrotoxicity in rats
Objective(s): Gentamicin is used for the treatment of Gram-negative bacterial infections. However, gentamicin administration is limited because of nephrotoxicity. The aim of the present study was to evaluate the protective effect of crocin against gentamicin-induced nephrotoxicity in rats. Materials and Methods: Thirty two male Wistar rats received gentamicin (100 mg/kg, IP), with or without c...
متن کاملEffects of Cinnamon Extract on Curing and Preventing Gentamicin-induced Nephrotoxicity in Immature White Rats
Background and purpose: Gentamicin-induced nephrotoxicity results from the production of reactive oxygen species (ROS) in the kidneys, and since cinnamon has antioxidant properties, this research studied the effects of cinnamon extract on the prevention and treatment of gentamicin-induced toxicity in immature white rats.Materials and methodology: in this study 36 immature female Wistar rats wer...
متن کاملEffect of normobaric hyperoxia on gentamicin-induced nephrotoxicity in rats
Objective(s):Gentamicin sulphate (GS) nephrotoxicity seems to be related to the generation of reactive oxygen species. There is evidence that oxygen preconditioning increases the activity of antioxidant enzymes. Materials and Methods: Forty eight female rats were divided into 6 groups (n=8) as follows: group 1 was the control, group 2 received daily GS, groups 3,4 and 5 received oxygen 2 hr/day...
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ژورنال
عنوان ژورنال: THE INDIAN JOURNAL OF VETERINARY SCIENCES AND BIOTECHNOLOGY
سال: 2017
ISSN: 2395-1176,2395-1176
DOI: 10.21887/ijvsbt.v13i01.8737